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Palpitations in the Emergency Department – A Complete NICE-Aligned Clinical Guide (2025)
By FrcemStudyZone editorial Team
18 Nov, 2025

Palpitations in the Emergency Department – A Complete NICE-Aligned Clinical Guide (2025)

© FRCEM Study Zone | Where Preparation Meets Precision

 www.FRCEMStudyZone.co.uk

Palpitations are one of the most common cardiovascular complaints presenting to both Emergency Departments and primary care. While often benign, they may represent serious arrhythmias, structural heart disease, or high-risk systemic conditions.

 For clinicians preparing for the Final FRCEM SBA examination, mastering the structured, guideline-based assessment of palpitations is essential.

This comprehensive guide integrates the latest NICE Clinical Knowledge Summary (CKS) recommendations on palpitations assessment, alongside Emergency Medicine considerations drawn from RCEM curriculum standards.

Primary source:

 🔗 NICE CKS – Palpitations (Assessment & Diagnosis)

 https://cks.nice.org.uk/topics/palpitations/diagnosis/assessment/


What Are Palpitations?

Palpitations describe an abnormal awareness of the heartbeat—whether fast, slow, irregular, forceful, or “fluttering.” They may occur in isolation or be associated with life-threatening cardiovascular pathology.

1. Taking a High-Value Clinical History (NICE CKS Guidance)

A structured, focused history is the most powerful diagnostic tool. NICE emphasises exploring:

✔ Circumstances before and during the episode

Onset during exercise is a red flag—consider malignant arrhythmias or structural heart disease.

Sudden onset/offset suggests SVT.

Irregular onset may suggest atrial fibrillation.

✔ Duration and frequency

Short, recurrent episodes often reflect SVT; prolonged episodes suggest AF, flutter, or sinus tachycardia.

✔ Nature of the rhythm

Ask the patient to tap out the rhythm—a simple, effective NICE-recommended method.

✔ Associated high-risk symptoms

Chest pain

Dyspnoea

Syncope or presyncope

Severe dizziness

These mandate urgent assessment and possible hospital referral.

✔ Past medical history

Conditions increasing arrhythmia risk include:

Ischaemic heart disease

Cardiomyopathy

Heart failure

Valve disease

✔ Family history

Sudden cardiac death <40 years is a major red flag (e.g., channelopathies).

✔ Lifestyle and drug factors

Palpitations may be triggered by:

Caffeine

Alcohol

Cocaine, amphetamines, cannabis

Nicotine

Prescribed & OTC medications (including β-agonists, decongestants, thyroxine)

✔ Systemic contributors

Thyrotoxicosis

Sepsis

Anaemia

Fever

Sleep deprivation

For full official guidance:

 🔗 NICE CKS – Palpitations History Taking

 https://cks.nice.org.uk/topics/palpitations/diagnosis/assessment/


2. Essential Examination (NICE & RCEM Standards)

A focused examination should include:

Cardiovascular assessment

Measure heart rate & rhythm

Blood pressure

Presence of murmurs

Signs of heart failure (JVP, basal crepitations, oedema)

Systemic assessment

Thyrotoxicosis (tremor, goitre, sweating)

Anaemia (pallor)

Sepsis indicators

If palpitations are ongoing, an immediate ECG is recommended.

3. ECG: Core to Diagnosis (NICE CKS & RCEM Curriculum)

Obtaining a 12-lead ECG is mandatory in current palpitations and recommended for all historical episodes.

Immediate ECG red flags

Ventricular tachycardia (VT) – Broad complex, rate >160 bpm

SVT – Narrow complex, regular, rate 140–280 bpm

Atrial fibrillation – Irregular, absent P-waves

Atrial flutter – Saw-tooth waves (≈300 bpm atrial rate)

WPW (pre-excitation) – Short PR, delta wave

Long QT syndrome – QTc >450 ms

Full ECG examples are available via NICE:

 🔗 NICE ECG Library

 https://cks.nice.org.uk/topics/palpitations/diagnosis/ecg-ft/

4. When to Admit – Emergency Red Flags (NICE)

Arrange emergency hospital admission if any of the following are present:

Current palpitations with:

Ventricular tachycardia

Persistent SVT

Haemodynamic instability

Chest pain or severe dyspnoea

High-risk ECG features (e.g., AV block, ischemic changes)

Palpitations triggered by exercise

Strong suspicious family history (e.g., SCD under age 40)

If trained, NICE advises attempting SVT termination manoeuvres before admitting:

Modified Valsalva

Carotid sinus massage (with continuous ECG monitoring and resuscitation facilities)

5. When to Refer to Cardiology

Urgent referral if:

Syncope or near syncope

Exercise-induced palpitations

Family history of sudden cardiac death (<40 years)

2nd- or 3rd-degree AV block

Routine referral for:

Episodes associated with chest pain or lightheadedness

Structural heart disease

Hypertension or heart failure

Recurrent SVT symptoms

Frequent ventricular ectopics

Suspected paroxysmal AF

6. Investigations in Primary Care

If admission is not indicated, NICE recommends:

Blood tests

FBC

U&E

Thyroid function

HbA1c

Liver function tests

Ambulatory monitoring

Daily symptoms → 24–48h Holter

Less frequent → event recorder

Rare, brief → patient instructed to obtain ECG at onset

Echocardiogram if:

Murmur present

HF suspected

ECG shows LVH, LBBB, pathological Q waves

7. Management Following Assessment

Benign palpitations

Reassure and provide lifestyle advice:

Reduce caffeine

Limit alcohol

Stop smoking

Reduce stress

Avoid recreational drugs

Atrial fibrillation or flutter

Refer to NICE AF guideline:

 🔗 NICE AF Guideline

 https://www.nice.org.uk/guidance/ng196


Extrasystoles

Reassure if no underlying heart disease.

Sinus tachycardia

Identify and treat the cause—fever, dehydration, anxiety, anaemia, pain.

8. Driving Advice (NICE & DVLA)

Group 1 (car/motorcycle)

Stop driving if arrhythmia may cause incapacity. Resume after the cause is controlled for 4 weeks.

Group 2 (bus/lorry)

Must stop driving and may resume only when controlled for 3 months.

🔗 DVLA Guide – Assessing Fitness to Drive

 https://www.gov.uk/guidance/assessing-fitness-to-drive-guide-for-medical-professionals

9. Final FRCEM SBA Exam Relevance

This topic directly aligns with the RCEM 2021 Curriculum (SLO 1, SLO 2, SLO 3) and appears frequently in Final FRCEM SBA examinations.

Key examinable areas include:

SVT recognition and management

VT vs SVT with aberrancy

WPW pattern vs syndrome

Long QT causes

AF red flags

ECG interpretation of arrhythmias

Admission criteria based on haemodynamic features

Ambulatory monitoring selection

Clinicians and exam candidates must recognise high-risk presentations promptly and understand when emergency admission is required.

Conclusion

Palpitations remain a challenging yet vital area of emergency and primary care practice. Using a NICE-aligned systematic approach, clinicians can differentiate benign symptoms from critical arrhythmias requiring urgent management.

For FRCEM candidates, mastering this topic ensures not only exam success but also enhanced clinical safety in the Emergency Department.

For more high-quality Final FRCEM resources, visit:

 👉 www.FRCEMStudyZone.co.uk

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