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Questions

 A 27-year-old woman presents to the Emergency Department with persistent gum bleeding since early morning and two spontaneous nosebleeds that occurred without trauma. She reports feeling “a bit off” today but has been otherwise well.

On examination, she has visible mucosal oozing, scattered petechiae over both shins, and dried blood around the nares. There is no splenomegaly or lymphadenopathy. Neurological examination is normal.

Her past medical history includes a previous admission during which she was treated with a short course of medication that “completely threw my mood off” and required specialist review. She also recalls receiving “an IV treatment for low platelets” during a hospital stay two years ago, which she says caused an immediate “bursting headache with vomiting” and was discontinued shortly after it began. She tells you she does not want anything similar again.

Observations: HR 104 bpm, BP 120/74 mmHg, RR 18/min, Temp 37.1°C, SpO₂ 99% RA.

Blood tests:

Platelets: 13 ×10⁹/L

Hb 118 g/L

WCC 7.5 ×10⁹/L

Coagulation normal

Blood film: normal with no fragments

ENT review her epistaxis and request urgent nasal packing. They ask you to arrange initial haematology treatment while they prepare.

Considering her presentation, select the MOST appropriate immediate therapy.

Which option is MOST appropriate?

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